‘Chagas Considered Emerging Global Disease’ – CSUF Researchers study spread of Plague to Parasites. Note, Kissing Bugs are cousins to Bed Bugs.

Back in 2011 we had alarming find: Bedbugs with ‘superbug’ germs MRSA and VRE

BBB

May 14, 2011 | by Christian Nordqvist | MNT, Medical News Today

Not only are there more bed bugs about in North America in Europe, but more of them appear to be carrying two types of superbugs – methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VRE) – bacteria that are resistant to antibiotics and very hard to treat when there is an infection.

Staph infection caused by MRSA is extremely difficult to treat because it is resistant to most antibiotics, including oxacillin, peicillin, methicillin, amoxicillin, and even methicillin.

VRE bacteria are resistant to vancomycin, an antibiotic. They are strains of the genus Enterococcus.

Bed bugs, also known as Cimex lectularius (Cimicidae) are tiny wingless insects that feed exclusively on the blood of warm-blooded animals, including humans. During their evolution they have become common nest parasites, infesting bird nests and bat roosts. Some bed bugs have learnt how to thrive in our nests, meaning our homes, and especially our beds. A baby bed bug is called a nymph and is about the size of a poppy seed. Adults reach about ¼ of an inch in length. They have an oval, flattened shape. Both adults and young are visible to the naked eye.

Bed bugs feed on us when we are asleep. As they feed we feel nothing, the process is painless. They inject a small amount of saliva into human skin while they feed. If they keep feeding on the same human night after night, that person can eventually develop a mild to intense allergic response to their saliva.

The study’s Canadian researchers wrote:

“Further studies are needed to characterize the association between S. aureus and bedbugs. Bed bug carriage of MRSA, and the portal of entry provided through feeding, suggests a plausible potential mechanism for passive transmission of bacteria during a blood meal. Because of the insect’s ability to compromise the skin integrity of its host, and the propensity for S. aureus to invade damaged skin, bed bugs may serve to amplify MRSA infections in impoverished urban communities.”
This latest report informs that the MRSA phenotype found in bed bugs is the same as those identified in many Eastside (Vancouver) patients infected with MRSA.

The scientists believe that the bed bugs probably promote the spread of MRSA in impoverished and overcrowded communities. The study took place in a poor part of Vancouver.

The researchers examined five bed bugs that had been taken from three patients staying at St. Paul’s Hospital – they all lived in Downtown Eastside, a poor part of Vancouver. In that part of Vancouver, MRSA infection incidence and cases of bed bugs had been rising steadily over the last few years. The scientists wanted to determine whether the two were linked.

They examined the bed bugs and found that three samples carried MRSA, while another two had VRE.

We still do not know whether the humans infected the bed bugs or the other way round. Further research is needed to determine where exactly on/in the bed bug the bacteria were – inside them or on their backs.

If bed bugs are able to carry and spread MRSA like the anopheles mosquito spreads malaria, we could be looking at a completely new vector of human disease.

Study author, Marc Romney, said:

“Even though this is a small study, it suggests that bedbugs may be playing a role in the transmission of MRSA in inner-city populations where bedbug infestations are a problem.”

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Woman warns – her dog was given ‘kiss of death’ from Kissing Bug bite

April 3, 2016 | by Nestor Mato | CBS 4 News

Many triatomine bugs carry the parasite Trypanosoma cruzi, which causes Chagas disease.

San Benito woman warns about potentially deadly Chagas disease spread by ‘kissing bug’

For Lisa Leal’s dog, a bug bite became the kiss of death.

A triatomine bug — commonly called a kissing bug — bit her 8-month-old dog.”I feel bad because she’s been given, literally, a death sentence,” said Leal, who lives in San Benito.

Many triatomine bugs carry the parasite Trypanosoma cruzi, which causes Chagas disease.

“The bugs are found in houses made from materials such as mud, adobe, straw, and palm thatch. During the day, the bugs hide in crevices in the walls and roofs,” according to the Centers for Disease Control and Prevention website. “During the night, when the inhabitants are sleeping, the bugs emerge. Because they tend to feed on people’s faces, triatomine bugs are also known as ‘kissing bugs.'”

Chagas disease may later cause intestinal and cardiac complications, including sudden death.

Leal’s dog is already suffering heart problems.

Veterinarian Noel Ramirez said there’s no sure way to avoid Chagas disease.

“It happens within city limits. It happens out in the country,” Ramirez said. “There’s not a whole lot of prevention that we can do.”

In humans, Chagas disease can be diagnosed with a blood test. Treatment varies depending on the symptoms.

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CDC Warns Tennessee Of Kissing Bug, deadly Chagas Disease

November 24, 2015 |NewsChannel 5

To prevent Kissing Bug  infestation the CDC recommends that you:

  • Seal cracks and gaps around windows, walls, roofs and doors
  • Remove wood, brush and rock piles near your house
  • Use screens on doors and windows and repair any holes or tears
  • Seal holes and cracks leading to the attic, crawl spaces below the house, and to the outside
  • Have pets sleep indoors, especially at night
  • Keep your house and any outdoor pet resting areas clean, in addition to periodically checking both areas for the presence of bugs
If you suspect you’ve found a kissing bug, the CDC says don’t squash it. Instead, place it in a container and fill with rubbing alcohol or freeze in water and take to your health department.

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11 things parents need to know about kissing bugs, aka ‘love bugs’ but are NOT, both ARE cousins to BedBug and deadly Chagas Disease

Baby_Chagas.jpg

December 4, 2015 | by Dr. Peter Hotez, President of Sabin Vaccine Institute

Experts at the National School of Tropical Medicine at Baylor College of Medicine have been studying Chagas disease and working on a therapeutic vaccine for it. Here are the important things to know about the kissing bug and about Chagas disease:

1.  Chagas disease, also known as American trypanosomiasis, is a serious infection caused by a parasitic microorganism, Trypanosoma cruzi, and is transmitted by kissing bugs.

2.  Chagas disease is a leading cause of heart disease resulting in a debilitating and often fatal condition known as Chagasic cardiomyopathy. One in six people with Chagasic cardiomyopathy will die within five years.

3.  An estimated 9 million people are infected in the Western Hemisphere, mostly in impoverished areas. According to the World Health Organization, the largest number of people living with Chagas disease are in poor areas of Argentina, Brazil and Mexico, while Bolivia has the highest percentage of people infected.

4.  The infection can be passed from mother to baby. There are an estimated 40,000 pregnant women in North America alone who have Chagas, and they will transmit the infection to their babies around 5 percent of the time.

5.  The CDC estimates that 300,000 cases occur in the United States, mostly imported from Latin America.

6.  Scientists at the National School of Tropical Medicine at Baylor, including Drs. Kristy Murray and Melissa Nolan Garcia, have uncovered a previously unrecognized level of transmission in the state of Texas.

7.  A high percentage of the kissing bugs in Texas are infected with the trypanosome parasite and show evidence of feeding on human blood.

8.  Dogs, cats and horses also can be infected.

9.  Researchers are finding cases among hunters and campers, as well as people who live in poverty in Texas. Those with extended outdoor exposure appear to have the greatest risk of acquiring the disease.

10.  Repeat exposures are likely necessary to acquire infection.

11.  Drug treatments are available, but they do not always work and are highly toxic. In collaboration with the Sabin Vaccine Institute and the Texas Children’s Hospital Center for Vaccine Development, the National School of Tropical Medicine is developing a new therapeutic vaccine for Chagas disease.

About Dr. Peter Hotez, president of Sabin Vaccine Institute: The US Science Envoy, Dean for the National School of Tropical Medicine, Texas Children’s Hospital Chair in Tropical Pediatrics and President-Sabin Vaccine Institute.

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Deadly Chagas Disease – Transmitted from Mother to Baby – Listen as Dr. Peter Hotez answers questions about neglected parasitic infections including deadly Chagas Disease

With the Center for Disease Control and Prevention naming five neglected parasitic infections as a priority for public health action, Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine, said he is excited about the “renewed commitment to control and prevent them.

“Houston and Texas in many respects represent ‘ground zero’ for many of America’s neglected tropical diseases, including parasitic infections,” said Hotez.  “We’re at the confluence of poverty and a subtropical climate – two of the major factors that promote these infections, which in reality are major health disparities in the United States. Unfortunately, these diseases have been overshadowed by better known infections, even though parasitic infections are much more common.”

The five infections include Chagas disease, cysticercosis, toxocariasis, toxoplasmosis and trichmoniasis. These diseases disproportionately affect Americans who live in extreme poverty and can cause serious illnesses including heart failure, pregnancy complications, seizures and even death.

Dr. Hotez responded to some questions about neglected parasitic infections and what is being done about them.
Hotez co-authored the opening editorial in the American Journal of Tropical Medicine and Hygiene, part of a series of articles that coincide with the CDC’s announcement to put focus on these neglected parasitic infections.

The National School of Tropical Medicine at Baylor College of Medicine was established in 2011 to address neglected tropical diseases and other infections through education, research and clinical care.

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Deadly Chagas disease in the U.S., affecting people and animals – primarily dogs. Watch out for “kissing bugs”, aka “love bugs”.

November 18, 2015 | by Robert Herriman | Outbreak News Today

Chagas disease, the parasitic infection caused by Trypanosoma cruzi, is found mainly in Latin America, where it is mostly transmitted to humans by the feces of triatomine bugs, known as “kissing bugs”.

The Triatoma or “kissing” bug. Image/CDC

However, in several areas of the United States Chagas is ever present, according to Dr. Peter Hotez, founding dean of the National School of Tropical Medicine at Baylor College of Medicine, who told me in 2013 the number of cases of Chagas disease in the United States to be somewhere between 300,000 and 1 million. The United States is ranked 7th among nations for the amount of cases.

Texas is definitely one state that is battling the neglected tropical disease. According to Texas health officials:

In Texas, approximately 45% of the collected triatomine bugs have tested positive for T. cruzi, and Chagas is considered an endemic disease in dogs. From 2013 to 2014, 351 cases of Chagas disease in animals, primarily dogs, were reported from approximately 20% of Texas counties, representing all geographic regions of the state. Locally-acquired human cases are uncommon, but some have been reported. From 2013 to 2014, 39 human cases of Chagas disease were reported: 24 were acquired in another country, 12 were locally-acquired, and the location of acquisition was unknown for 3.

Local transmission means that the kissing bugs in Texas are infected with the parasite, causing it to spread to humans.

Chagas disease is transmitted naturally in North, Central, and South America. In parts of Mexico and Central and South America, where Chagas disease is considered highly endemic, it is estimated that approximately 8 million people are infected.

Chagas in Texas/Texas Department of Health

The Triatoma or “kissing” bug frequently carry for life the parasite, Trypanosoma cruzi. T. cruzi is a comma shaped flagellated parasite and the cause of an acute and chronic disease called Chagas.

The triatoma bug can be found in poorly constructed homes, with cracks and crevices in the walls or those with thatch roofs. They can also be found in palm trees and the fronds.

Usually at night while sleeping, the insect feeds on people or other mammals. While feeding the insect defecates and the infected feces gets rubbed into the bite wound, eyes abrasions or other skin wounds.

The parasite invades macrophages at or near the site of entry. Here they transform, multiply and rupture from the cells 4-5 days later and enter the blood stream and tissue spaces.

Initial infection with Chagas is typically asymptomatic. Acute disease may manifest symptoms after a couple of weeks.

Reddening of the skin (Chagoma) or edema around the eye (Romana’s sign) may be seen, albeit uncommon.

Fever, malaise, enlarged liver and spleen are part of the acute syndrome. 10% of people develop acute myocaditis with congestive heart failure. This acute disease can be fatal.

After a latent period which may last for years, the infected person may develop chronic disease (20-40%). The most serious consequences are cardiomyopathy (in certain areas it’s the leading cause of death in men less than 45 years of age) and megacolon/megaesophogus.

Trypanosoma cruzi can also be transmitted via congenital transmission (mother to baby), through blood transfusions and organ transplants, and some cases of transmission through feces contaminated food.

About 150 mammals beside humans may serve as reservoirs of the parasite. Dogs, cats, opossoms and rats are among the animals.

Benznidazole and nifurtimox are 100 percent effective in killing the parasite and curing the disease, but only if given soon after infection at the onset of the acute phase, according to the WHO.

There is no vaccine for Chaga’s, so preventive measures should include insecticide spraying of infested houses.

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Watch the lifecycle of parasite that causes deadly Chagas disease – transmitted by the Kissing Bug…aka the Love Bug – both cousins to the BedBug

The cause of Chagas disease is the parasite Trypanosoma cruzi, which is transmitted to humans from a bite from an insect known as the triatomine bug. These insects can become infected by T. cruzi when they ingest blood from an animal already infected with the parasite.
This video was produced by Dirceu Esdras Teixeira, Marlene Benchimol, Wanderley de Souza and Paul Crepaldi on August 30, 2012.

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BedBugs reported in some of NYC’s swankiest hotels. They were always there; and it’s getting worse. More important to follow as BedBugs transmit deadly Chagas disease.

February 8, 2016 | by Leonard Greene | New York Daily News
It’s not just the fleabags and flophouses.

Bedbugs have been reported in some of the city’s swankiest hotels with a list that includes the Waldorf Astoria the Millennium Hilton and the New York Marriott Marquis.

According to the Bedbug Registry, a nationwide database of bedbug reports and complaints, bedbug sightings in New York hotels have jumped more than 44 percent between 2014 and 2015.

The Millenium Hilton at 55 Church Street in New York New York.
Google Maps Street View

The Millenium Hilton at 55 Church Street in New York New York.

The data focused on establishments that are members of the Hotel Association of New York City.

Of the 272 association members, 65 percent, or 176 members, have had a guest file at least one complaint about bedbugs at the property.

NR

Michelle Bennett/Getty Images/Lonely Planet Image

Taxi cabs outside Waldorf Astoria Hotel.

Eighteen hotels had a combined 363 complaints, representing 42 percent of all bedbug complaints.

“I stayed in room 2306 for one night,” a Millennium Hilton guest wrote in a complaint to the hotel in 2014. “I found blood on my sheets and a live bug on my bed. I ended up with 60 plus bites.”

At the Times Square Doubletree guest said a stay there last year left hundreds of bite marks on the face, neck arms and hands.

“Extreme case of bed bug attacked on my entire upper body,” the guest wrote.” Went home to Florida a day early and ended up in my local emergency room.”

Research Entomologist Jeffrey White shows off some bedbugs at a informational bedbug conference at 201 Mulberry Street in Manhattan Wednesday.

Warga, Craig/New York Daily News

Last month, a California couple posted a YouTube video about their $400-a-night Central Park hotel room nightmare. The couple found dozens of bedbugs beneath their mattress at the Astor on the Park Hotel.

Lisa Linden, a spokeswoman for the hotel association, said hotels in New York are addressing the issue.

“Bedbugs are a global issue that extend beyond hotels,” Linden said.

”Every member of the Hotel Association of NYC that we are aware of has an active anti-bedbug program in place. If a problem arises, it is dealt with immediately and effectively.”

Scientists who recently studied the bloodsucking creatures in the city’s subway system discovered a genetic diversity among bedbugs depending upon the neighborhood where they were found.

They said the discovery could lead to better insecticides.

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California study examines genetic diversity of Kissing Bugs…concludes deadly Chagas disease may be underdiagnosed in U.S.

January 21, 2016 | MedicalXpress.com

Trypanosoma cruzi is a protozoan parasite that can cause an insidious onset of Chagas disease, a fatal cardiac disease in humans and dogs. The parasite is transmitted via triatomine insects, commonly called kissing bugs. In Latin America T. cruzi is recognized as an economically important parasite; however, there is limited research regarding its spread and virulence in the USA. As a result, while the genetic diversity of the T. cruzi parasite has been well studied in Latin America less is known about the strains endemic to the USA.

“Chagas disease should be considered as a potential cause of cardiac illness in humans and dogs.”

Researchers from the University of California, Davis, and the London School of Hygiene and Tropical Medicine assessed the prevalence of T. cruzi from northern and southern California regions. The researchers used a combination of methods to obtain triatomine insects, including active collection via black light traps and the enlistment of private property owners and public health officials in specimen submission. DNA was extracted from the specimens and screened for T. cruzi via molecular techniques. Positive samples were genetically typed into one of six recognized T. cruzi subgroups (TcI – TcVI). Finally, the researchers performed genetic analyses to examine the potential virulence of the California T. cruzi samples as compared to infective T. cruzi strains from Latin America.

Of the 29 specimens from northern California 55% were infected, while T. cruzi was detected in 34% of the 53 samples collected from one of the southern California locations. Two separate subtypes were found—with 20 parasites falling into the TcI subgroup and 2 into TcIV. The TcIV subgroup was not detected in the northern California region. Genetic analyses did not reveal any particular unique characteristics to distinguish the California samples from several Latin American strains known to infect humans.

This research suggests that the apparent rarity of locally-acquired Chagas disease in the USA is unlikely due to any genetic difference in the infectious capabilities of the parasite. Rather, the fact that local triatomine species (e.g. Triatoma protracta) do not frequently colonize human homes, likely translates to decreased T. cruzi transmission. Alternatively, locally-acquired Chagas disease may simply be underdiagnozed. At present only four states in the USA list Chagas disease as a reportable illness, and California is not among them. This means that the public, as well as physicians and veterinary practitioners, may have decreased awareness of the dangers posed by this disease.

Based on this research, in areas where Triatoma protracta populations are evident, Chagas disease should be considered as a potential cause of cardiac illness in humans and dogs.

The study is published in PLOS Neglected Tropical Diseases.